Aging Methods and Protocols by Yvonne A. Barnett, Christopher R. Barnett

By Yvonne A. Barnett, Christopher R. Barnett

Getting older tools and Protocols offers a few cutting-edge protocols, defined by way of well-known specialists of their box, that are getting used to additional our knowing of the getting older technique. those distinctive biochemical, actual and molecular biology strategies are mixed to supply an exceptional source for researchers and scientists from a large choice of disciplines. additionally integrated is a presentation of 2 case reviews that target the position of nutritional restrict in lifestyles span extension, in addition to how one can determine and make the most of transgenic animals for the elucidation of the molecular points of getting older. This ebook is a useful resource of state of the art study protocols with wide medical applicability and may curiosity clinical researchers, clinicians concerned inIn this paintings, specialists aspect key biochemical, analytical, and molecular options for the research of getting older on the mobile, tissue, organ, and full process degrees.

Show description

Read or Download Aging Methods and Protocols PDF

Similar geriatrics books

Macular degeneration

 Macular Degeneration: technology & drugs in perform presents a distinct assessment of present pondering within the pathogenesis, occurrence and therapy of AMD. It contains, for the 1st time, a synthesis of the perspectives of the world's top scientists and practitioners concerning retinal biology, easy mechanisms, scientific and pathogenetic strategies, and rational methods to intervention.

The Social Behavior of Older Animals

How do old and young social animals view one another? Are elderly animals perceived by way of others as weaker? Or wiser? what's the dating among age and tool between social animals? Taking a cue from Frans de Waal's seminal paintings reading the lives of chimpanzees, Anne Innis Dagg during this pioneering examine probes the lives of older mammals and birds.

Primary Care Geriatrics: A Case-Based Approach, 5e

Designed for somebody all for treating geriatric sufferers, this new version is still the easiest finished resource for medical options for the tough geriatric inhabitants. within, you will discover a wealth of data at the rules of geriatric basic care. .. targeted, case-based ways to significant geriatric syndromes.

Women over 50: Psychological Perspectives

This ebook analyzes the demanding situations, advantages, coping suggestions, difficulties, and accomplishments linked to the midlife adventure of ladies. Ten chapters current the country of analysis (and right longstanding myths) relating to major features of middle-aged women's lives. The ebook bridges a big wisdom hole within the feminist-psychology literature.

Additional resources for Aging Methods and Protocols

Sample text

The square root of 400 (20) is 5%, which is the limit of statistical reliability for most biological work. Record the number of cells and the number of fields counted. The cell density is then calculated as follows: cell density = (no. of cells counted)/([no. 6. 1. Coverslips 1. Place coverslips in a clean, glass rack using forceps. 2. Lower the rack containing the coverslips into a solution of chloroform/95% ethanol (1:1) and allow to soak for 30 min. 3. Rinse the coverslips with deionized water.

And Smith, J. R. (1995) Identification of the active region of the DNA synthesis inhibitory gene p21Sdi1/CIP1/WAF1. EMBO J. 14, 555–563. 102. Allen, R. , Keogh, B. , and Cristofalo, V. J. (1995) Expression and regulation of SOD activity in human skin fibroblasts from donors of different ages. J. Cell. Physiol. 165, 576–587. 103. , Millis, A. J. , and Baglioni, C. (1992) Expression of interleukin 1-inducible genes and production of interleukin 1 by aging human fibroblasts. Proc. Natl. Acad. Sci.

27. , and Yamakido, M. (1995) Alterations in telomeric repeat length in lung cancer are associated with loss of heterozygosity in p53 and Rb. Oncogene 10, 937–944. 28. Goldstein, S. and Harley, C. B. (1979) In vitro studies of age-associated diseases. Fed. Proc. 38, 1862–1867. 29. Brown, W. T. (1990) Genetic diseases of premature aging as models of senescence, in Annual Review of Gerontology and Geriatrics, vol. 10 (Cristofalo, V. J. and Lawton, M. ), Springer, New York, pp. 23–52. 30. Bodnar, A.

Download PDF sample

Rated 4.13 of 5 – based on 47 votes