Amyotrophic Lateral Sclerosis by Hiroshi Mitsumoto MD

By Hiroshi Mitsumoto MD

Amyotrophic Lateral Sclerosis provides the main entire, clinically-focused info on ALS (Lou Gehrig's ailment) in print. the 3 authors, widely recognized for his or her paintings during this sector, offer cohesive and balanced assurance of this syndrome, together with the heritage, scientific positive aspects, pathology and pathogenesis, therapy and administration of ALS. To facilitate knowing, each one bankruptcy is greater via entire tables and figures, in addition to certain bankruptcy summaries.

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50 The 11 patients whom Aran originally described were also seen by Duchenne for galvanic electric therapy. In his 1850 report, Aran acknowledged Duchenne, saying, "I have a thousand obligations to my friend M. le Dr. 17 Strongly influenced by Duchenne, Aran reversed his earlier opinion and concluded in his paper of 1850 that PMA was caused by a muscle disease. Thereafter, Aran's interest in and commitment to neurology waned. Duchenne, on the other hand, contributed enormously to the field, and credit for the description of PMA was associated more with Duchenne than Aran.

Gax Hebd Med Chir 6:390-392, 1859. 21. Engel, WK, Kurland, LT, and Klatzo, I: An inherited disease similar to amyotrophic lateral sclerosis with a pattern of posterior column involvement. An intermediate form? Brain 82:203-222, 1959. 22. Erb, WH: Uber einen wenig bekannten spinalen symptomen-complex. Berl Klin Wochenschr 12:357-359, 1875. 23. Finger, S: Origin of neuroscience. A history of explorations into brain function. Oxford University Press, New York, 1994. 24. Fromann, M: Atrophie musculaire progressive (autopsie).

Arnold, London, 1958, pp 545-548. 30. Haymaker, W and Schiller, F: The Founders of Neurology, ed 2. Charles C Thomas, Springfield, IL, 1970. 31. Heitzman, D, Wilbourn, A, and Mitsumoto, H: A retrospective study examining the clinical and electrodiagnostic features of patients with bulbar-onset amyotrophic lateral sclerosis. Neurology 45(suppl 4):A447, 1995. 32. Hirano, A, Kurland, LT, Krooth, RS, et al: Parkinsonism-dementia complex, an endemic disease on the island of Guam. I. Clinical features.

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